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Reconstitution of Mdm2-Dependent Post-Translational Modifications of p53 in Yeast
p53 mediates cell cycle arrest or apoptosis in response to DNA damage. Its activity is subject to a tight regulation involving a multitude of post-translational modifications. The plethora of functional protein interactions of p53 at present precludes a clear understanding of regulatory principles i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200829/ https://ncbi.nlm.nih.gov/pubmed/18231594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001507 |
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