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Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate

BACKGROUND: Pleckstrin homology (PH) domains are one of the most prevalent domains in the human proteome and represent the major phosphoinositide-binding module. These domains are often found in signaling proteins and function predominately by targeting their host proteins to the cell membrane. Inos...

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Hlavní autoři: Jackson, Sean G, Zhang, Yi, Haslam, Richard J, Junop, Murray S
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200656/
https://ncbi.nlm.nih.gov/pubmed/18034889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-80
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