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Locally applied Simvastatin improves fracture healing in mice
BACKGROUND: HMG-CoA reductase inhibitors, statins, are widely prescribed to lower cholesterol. High doses of orally administered simvastatin has previously been shown to improve fracture healing in a mouse femur fracture model. In this study, simvastatin was administered either subcutaneously or dir...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200653/ https://ncbi.nlm.nih.gov/pubmed/17897477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-8-98 |
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