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Locally applied Simvastatin improves fracture healing in mice

BACKGROUND: HMG-CoA reductase inhibitors, statins, are widely prescribed to lower cholesterol. High doses of orally administered simvastatin has previously been shown to improve fracture healing in a mouse femur fracture model. In this study, simvastatin was administered either subcutaneously or dir...

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Hlavní autoři: Skoglund, Björn, Aspenberg, Per
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200653/
https://ncbi.nlm.nih.gov/pubmed/17897477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-8-98
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