Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD

BACKGROUND: Smoking activates and recruits inflammatory cells and proteases to the airways. Matrix metalloproteinase (MMP)-12 may be a key mediator in smoke induced emphysema. However, the influence of smoking and its cessation on airway inflammation and MMP-12 expression during COPD is still unknow...

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Main Authors: Babusyte, Agne, Stravinskaite, Kristina, Jeroch, Jolanta, Lötvall, Jan, Sakalauskas, Raimundas, Sitkauskiene, Brigita
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200652/
https://ncbi.nlm.nih.gov/pubmed/18001475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-81
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