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Ligation of CR1 (C3b receptor, CD35) on CD4(+) T lymphocytes enhances viral replication in HIV-infected cells

The present study provides evidence for a role of the C3b receptor, CR1 (CD35), in activation of HIV replication in CD4(+) T lymphocytes. Ligation of CR1 with cross-linked anti-receptor MoAbs or with aggregated C3b enhanced transcription of viral genes and the release of p24 and RT activity from cul...

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Hlavní autoři: MOUHOUB, A, DELIBRIAS, C C, FISCHER, E, BOYER, V, KAZATCHKINE, M D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200595/
https://ncbi.nlm.nih.gov/pubmed/8918576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-844.x
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