Intracellular cytokine production by human CD4(+) and CD8(+) T cells from normal and immunodeficient donors using directly conjugated anti-cytokine antibodies and three-colour flow cytometry

Antzeko izenburuak

• Primary defect in CD8(+) lymphocytes in the antibody deficiency disease (common variable immunodeficiency): abnormalities in intracellular production of interferon-gamma (IFN-γ) in CD28(+) (‘cytotoxic’) and CD28(−) (‘suppressor’) CD8(+) subsets
  nork: North, M E, et al.
  Argitaratua: (1998)
• Effects of 17 beta-oestradiol on function of lymphocytes from normal donors and patients with common variable immunodeficiency (CVID).
  nork: Evagelatou, M, et al.
  Argitaratua: (1994)
• Co-stimulation with anti-CD28 (Kolt-2) enhances DNA synthesis by defective T cells in common variable immunodeficiency.
  nork: North, M E, et al.
  Argitaratua: (1994)
• Raised serum levels of CD8, CD25 and beta 2-microglobulin in common variable immunodeficiency.
  nork: North, M E, et al.
  Argitaratua: (1991)
• Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells.
  nork: Funauchi, M, et al.
  Argitaratua: (1995)