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Autoantibodies that stabilize the molecular interaction of Ku antigen with DNA-dependent protein kinase catalytic subunit

DNA-dependent protein kinase (DNA-PK) consists of a DNA binding subunit (Ku autoantigen), and a catalytic subunit (DNA-PK(cs)). In the present study, human autoantibodies that recognize novel antigenic determinants of DNA-PK were identified. One type of autoantibody stabilized the interaction of DNA...

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Détails bibliographiques
Auteurs principaux: SATOH, M, AJMANI, A K, STOJANOV, L, LANGDON, J J, OGASAWARA, T, WANG, J, DOOLEY, M A, RICHARDS, H B, WINFIELD, J B, CARTER, T H, REEVES, W H
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200543/
https://ncbi.nlm.nih.gov/pubmed/8809135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-775.x
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