Human monoclonal rheumatoid factors augment arthritis in mice by the activation of T cells

In order to investigate the in vivo role of rheumatoid factor (RF), the effects of the administration of human monoclonal (m) IgM-RF and IgG-RF on the development of arthritis in mice were examined. The administration of human mRFs into mice immunized with type II collagen (CII) markedly enhanced th...

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Detalhes bibliográficos
Main Authors: EZAKI, I, OKADA, M, YOSHIKAWA, Y, FUJIKAWA, Y, HASHIMOTO, M, OTSUKA, M, NOMURA, T, YAMAMOTO, K, WATANABE, T, SHINGU, M, NOBUNAGA, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1996
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200454/
https://ncbi.nlm.nih.gov/pubmed/9099933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.55764.x
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