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Autoantibodies to the collagenous region of C1q occur in three strains of lupus-prone mice

We have developed an ELISA to measure murine autoantibodies to the collagenous region (CLR) of C1q, using the whole human C1q molecule as the solid-phase ligand, in the presence of 1 m NaCl. The assay was validated by testing positive sera from 20 mice using purified mouse C1q, and from 10 mice usin...

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Detalhes bibliográficos
Main Authors: HOGARTH, M B, NORSWORTHY, P J, ALLEN, P J, TRINDER, P K E, LOOS, M, MORLEY, B J, WALPORT, M J, DAVIES, K A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200417/
https://ncbi.nlm.nih.gov/pubmed/8625515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.19725.x
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