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Anti-DNA antibody derived from a systemic lupus erythematosus (SLE) patient forms histone–DNA–anti-DNA complexes that bind to rat glomeruli in vivo

Histone can mediate the binding of both free DNA and DNA complexed to anti-DNA antibody to the glomerular capillary wall. We tested whether preformed histone–DNA–anti-DNA immune complexes (IC) could bind to the glomerular capillary wall. The immune complex, generated with anti-DNA antibody derived f...

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Autores principales: MORIOKA, T, FUJIGAKI, Y, BATSFORD, S R, WOITAS, R, OITE, T, SHIMIZU, F, VOGT, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200408/
https://ncbi.nlm.nih.gov/pubmed/8603540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-658.x
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