The frequent mutation Gly/Asp in CDR1H may determine a cross-reactive idiotope in anti-I cold agglutinins

Variable domains (V(H)) of all known anti i/I cold agglutinin (CA) heavy chains are codified by the V(H)4–21 gene. While anti-i CAs are the expression of gene rearrangement without mutations represented by amino acid changes, anti-I CAs present, among others, a frequent somatic mutation of Gly by As...

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Bibliographic Details
Main Authors: ABATANGELO, C, PLOTKIN, L, MATHOV, I, SQUIQUERA, L, LEONI, J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1996
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200402/
https://ncbi.nlm.nih.gov/pubmed/8603526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-653.x
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