Human XIST yeast artificial chromosome transgenes show partial X inactivation center function in mouse embryonic stem cells

Initiation of X chromosome inactivation requires the presence, in cis, of the X inactivation center (XIC). The Xist gene, which lies within the XIC region in both human and mouse and has the unique property of being expressed only from the inactive X chromosome in female somatic cells, is known to b...

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Main Authors: Heard, Edith, Mongelard, Fabien, Arnaud, Danielle, Chureau, Corinne, Vourc’h, Claire, Avner, Philip
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC22003/
https://ncbi.nlm.nih.gov/pubmed/10359800
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