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Genetic analysis of the requirements for SOS induction by nalidixic acid in Escherichia coli
Nalidixic acid, the prototype antibacterial quinolone, induces the SOS response by a mechanism that requires the RecBCD nuclease/helicase. A key step inferred for this induction pathway is the conversion of a drug-induced gyrase cleavage complex into a DNA break that can be processed by RecBC. We tr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200294/ https://ncbi.nlm.nih.gov/pubmed/16005583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2005.04.029 |
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