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The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein

Membrane-anchored forms of the v-sis oncoprotein have been previously described which are oriented as type I transmembrane proteins and which efficiently induce autocrine transformation. Several examples of naturally occurring membrane-anchored growth factors have been identified, but all exhibit a...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200122/
https://ncbi.nlm.nih.gov/pubmed/8227125
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