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Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL

Vibrio cholerae and Escherichia coli heat labile toxins (CT and LT) elicit a secretory response from intestinal epithelia by binding apical receptors (ganglioside GM1) and subsequently activating basolateral effectors (adenylate cyclase). We have recently proposed that signal transduction in polariz...

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Detalles Bibliográficos
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200010/
https://ncbi.nlm.nih.gov/pubmed/7490296
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