Essential Role of Voltage-Dependent Anion Channel in Various Forms of Apoptosis in Mammalian Cells

Through direct interaction with the voltage-dependent anion channel (VDAC), proapoptotic members of the Bcl-2 family such as Bax and Bak induce apoptogenic cytochrome c release in isolated mitochondria, whereas BH3-only proteins such as Bid and Bik do not directly target the VDAC to induce cytochrom...

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Bibliografske podrobnosti
Main Authors: Shimizu, Shigeomi, Matsuoka, Yosuke, Shinohara, Yasuo, Yoneda, Yoshihiro, Tsujimoto, Yoshihide
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2001
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199613/
https://ncbi.nlm.nih.gov/pubmed/11266442
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