Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148

Confluent endothelial cells respond poorly to the proliferative signals of VEGF. Comparing isogenic endothelial cells differing for vascular endothelial cadherin (VE-cadherin) expression only, we found that the presence of this protein attenuates VEGF-induced VEGF receptor (VEGFR) 2 phosphorylation...

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Auteurs principaux: Lampugnani, Maria Grazia, Zanetti, Adriana, Corada, Monica, Takahashi, Takamune, Balconi, Giovanna, Breviario, Ferruccio, Orsenigo, Fabrizio, Cattelino, Anna, Kemler, Rolf, Daniel, Thomas O., Dejana, Elisabetta
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199373/
https://ncbi.nlm.nih.gov/pubmed/12771128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209019
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