Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae

Procollagen (PC)-I aggregates transit through the Golgi complex without leaving the lumen of Golgi cisternae. Based on this evidence, we have proposed that PC-I is transported across the Golgi stacks by the cisternal maturation process. However, most secretory cargoes are small, freely diffusing pro...

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Autori principali: Mironov, Alexander A., Beznoussenko, Galina V., Nicoziani, Paolo, Martella, Oliviano, Trucco, Alvar, Kweon, Hee-Seok, Di Giandomenico, Daniele, Polishchuk, Roman S., Fusella, Aurora, Lupetti, Pietro, Berger, Eric G., Geerts, Willie J.C., Koster, Abraham J., Burger, Koert N.J., Luini, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199327/
https://ncbi.nlm.nih.gov/pubmed/11756473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108073
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