Polyploids require Bik1 for kinetochore–microtubule attachment

The attachment of kinetochores to spindle microtubules (MTs) is essential for maintaining constant ploidy in eukaryotic cells. Here, biochemical and imaging data is presented demonstrating that the budding yeast CLIP-170 orthologue Bik1is a component of the kinetochore-MT binding interface. Striking...

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Bibliografiske detaljer
Main Authors: Lin, Haijiang, de Carvalho, Pedro, Kho, David, Tai, Chin-Yin, Pierre, Philippe, Fink, Gerald R., Pellman, David
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199317/
https://ncbi.nlm.nih.gov/pubmed/11756471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108119
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