Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-γ

BACKGROUND: Various lines of evidence have shown that bisphenol A [BPA; HO-C(6)H(4)-C(CH(3))(2)-C(6)H(4)-OH] acts as an endocrine disruptor when present in very low doses. We have recently demonstrated that BPA binds strongly to human estrogen-related receptor-γ (ERR-γ ) in a binding assay using [(3...

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Autors principals: Okada, Hiroyuki, Tokunaga, Takatoshi, Liu, Xiaohui, Takayanagi, Sayaka, Matsushima, Ayami, Shimohigashi, Yasuyuki
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2008
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199305/
https://ncbi.nlm.nih.gov/pubmed/18197296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10587
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