Abnormal melatonin synthesis in autism spectrum disorders

Melatonin is produced in the dark by the pineal gland and is a key regulator of circadian and seasonal rhythms. A low melatonin level was reported in individuals with autism spectrum disorders (ASD), but the underlying cause of this deficit was unknown. The ASMT gene, encoding the last enzyme of mel...

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Auteurs principaux: Melke, Jonas, Goubran-Botros, Hany, Chaste, Pauline, Betancur, Catalina, Nygren, Gudrun, Anckarsäter, Henrik, Rastam, Maria, Ståhlberg, Ola, Gillberg, I. Carina, Delorme, Richard, Chabane, Nadia, Mouren-Simeoni, Marie-Christine, Fauchereau, Fabien, Durand, Christelle M., Chevalier, Fabien, Drouot, Xavier, Collet, Corinne, Launay, Jean-Marie, Leboyer, Marion, Gillberg, Christopher, Bourgeron, Thomas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group Specialist Journals 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199264/
https://ncbi.nlm.nih.gov/pubmed/17505466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mp.4002016
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