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Assembly and function of AP-3 complexes in cells expressing mutant subunits

The mouse mutants mocha and pearl are deficient in the AP-3 δ and β3A subunits, respectively. We have used cells from these mice to investigate both the assembly of AP-3 complexes and AP-3 function. In mocha cells, the β3 and μ3 subunits coassemble into a heterodimer, whereas the σ3 subunit remains...

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Detalhes bibliográficos
Main Authors: Peden, Andrew A., Rudge, Rachel E., Lui, Winnie W.Y., Robinson, Margaret S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199225/
https://ncbi.nlm.nih.gov/pubmed/11807095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200107140
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