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Induction of Apoptosis of Metastatic Mammary Carcinoma Cells In Vivo by Disruption of Tumor Cell Surface CD44 Function

To understand how the hyaluronan receptor CD44 regulates tumor metastasis, the murine mammary carcinoma TA3/St, which constitutively expresses cell surface CD44, was transfected with cDNAs encoding soluble isoforms of CD44 and the transfectants (TA3sCD44) were compared with parental cells (transfect...

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Detalhes bibliográficos
Main Authors: Yu, Qin, Toole, Bryan P., Stamenkovic, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199167/
https://ncbi.nlm.nih.gov/pubmed/9396767
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