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Antigen Presentation by Dendritic Cells after Immunization with DNA Encoding a Major Histocompatibility Complex Class II–restricted Viral Epitope

Intramuscular and intracutaneous immunization with naked DNA can vaccinate animals to the encoded proteins, but the underlying mechanisms of antigen presentation are unclear. We used DNA that encodes an A/PR/8/34 influenza peptide for CD4 T cells and that elicits protective antiviral immunity. DNA-t...

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Detalhes bibliográficos
Main Authors: Casares, Sofia, Inaba, Kayo, Brumeanu, Teodor-Doru, Steinman, Ralph M., Bona, Constantin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199124/
https://ncbi.nlm.nih.gov/pubmed/9348305
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