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pH-dependent Perforation of Macrophage Phagosomes by Listeriolysin O from Listeria monocytogenes

The pore-forming toxin listeriolysin O (LLO) is a major virulence factor implicated in escape of Listeria monocytogenes from phagocytic vacuoles. Here we describe the pH-dependence of vacuolar perforation by LLO, using the membrane-impermeant fluorophore 8-hydroxypyrene-1,3,6-trisulfonic acid (HPTS)...

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Autors principals: Beauregard, Kathryn E., Lee, Kyung-Dall, Collier, R. John, Swanson, Joel A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199064/
https://ncbi.nlm.nih.gov/pubmed/9314564
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