Negative Signaling Pathways of the Killer Cell Inhibitory Receptor and FcγRIIb1 Require Distinct Phosphatases

Inhibition of natural killer (NK) cells by the killer cell inhibitory receptor (KIR) involves recruitment of the tyrosine phosphatase SHP-1 by KIR and is prevented by expression of a dominant negative SHP-1 mutant. Another inhibitory receptor, the low affinity Fc receptor for immunoglobulin G (IgG)...

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Hlavní autoři: Gupta, Neetu, Scharenberg, Andrew M., Burshtyn, Deborah N., Wagtmann, Nicolai, Lioubin, Mario N., Rohrschneider, Larry R., Kinet, Jean-Pierre, Long, Eric O.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199004/
https://ncbi.nlm.nih.gov/pubmed/9236201
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