An Interleukin 5 Mutant Distinguishes between Two Functional Responses in Human Eosinophils

Interleukin 5 (IL-5) is the key cytokine involved in regulating the production and many of the specialized functions of mature eosinophils including priming, adhesion, and survival. We have generated a point mutant of human IL-5, IL-5 (E12K), which is devoid of agonist activity in both a TF-1 cell p...

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Main Authors: McKinnon, Murray, Page, Kevin, Uings, Iain J., Banks, Martyn, Fattah, Dilniya, Proudfoot, Amanda E.I., Graber, Pierre, Arod, Christian, Fish, Richard, Wells, Timothy N.C., Solari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198963/
https://ncbi.nlm.nih.gov/pubmed/9207003
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