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Interleukin 12 (IL-12) Is Crucial to the Development of Protective Immunity in Mice Intravenously Infected with Mycobacterium tuberculosis

Immunity to Mycobacterium tuberculosis infection is associated with the emergence of protective CD4 T cells that secrete cytokines, resulting in activation of macrophages and the recruitment of monocytes to initiate granuloma formation. The cytokine-mediating macrophage activation is interferon-γ (I...

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Hlavní autoři: Cooper, Andrea M., Magram, Jeanne, Ferrante, Jessica, Orme, Ian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198958/
https://ncbi.nlm.nih.gov/pubmed/9206995
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