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Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease

Alzheimer disease (AD) is characterized by the presence of plaques and tangles in parallel with progressive cognitive decline. The underlying cause of the cognitive decline is unknown. The purpose of this study was to identify factors that could affect learning and memory using the Tg2576 mouse mode...

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Autori principali: Parachikova, A., Cotman, C.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198928/
https://ncbi.nlm.nih.gov/pubmed/17764962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.07.001
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