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Catechol-O-methyltransferase: Effects of the Val108Met polymorphism on protein turnover in human cells

A single nucleotide polymorphism in the human COMT (catechol-O-methyltransferase) gene has been associated with increased risk for breast cancer and several CNS diseases and disorders. The G to A polymorphism causes a valine (val) to methionine (met) substitution at codon 108 soluble- (S)/ 158 membr...

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Autores principales: Doyle, Anne E., Yager, James D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198850/
https://ncbi.nlm.nih.gov/pubmed/17980711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2007.10.002
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