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Catechol-O-methyltransferase: Effects of the Val108Met polymorphism on protein turnover in human cells
A single nucleotide polymorphism in the human COMT (catechol-O-methyltransferase) gene has been associated with increased risk for breast cancer and several CNS diseases and disorders. The G to A polymorphism causes a valine (val) to methionine (met) substitution at codon 108 soluble- (S)/ 158 membr...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2198850/ https://ncbi.nlm.nih.gov/pubmed/17980711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2007.10.002 |
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