Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.

Ítems similars

• Insensitivity of Bacteria to Proposed Antimetabolites of d-Alanyl-d-Alanine
  per: Gale, Glen R., et al.
  Publicat: (1973)
• Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases.
  per: Yocum, R R, et al.
  Publicat: (1979)
• Modifications of the acyl-d-alanyl-d-alanine terminus affecting complex-formation with vancomycin
  per: Nieto, M., et al.
  Publicat: (1971)
• Utilization of a depsipeptide substrate for trapping acyl—enzyme intermediates of penicillin-sensitive D-alanine carboxypeptidases
  per: Rasmussen, James R., et al.
  Publicat: (1978)
• Active-site-serine D-alanyl-D-alanine-cleaving-peptidase-catalysed acyl-transfer reactions. Procedures for studying the penicillin-binding proteins of bacterial plasma membranes.
  per: Ghuysen, J M, et al.
  Publicat: (1986)