Tumor pH-responsive flower-like micelles of poly(L-lactic acid)-b-poly(ethylene glycol)-b-poly(L-histidine)

Polymeric micelles were constructed from poly(L-lactic acid) (PLA; M(n) 3K)-b-poly(ethylene glycol) (PEG; M(n) 2K)-b-poly(L-histidine) (polyHis; M(n) 5K) as a tumor pH-specific anticancer drug carrier. Micelles (particle diameter: ~ 80 nm; critical micelle concentration (CMC): 2 µg/ml) formed by dia...

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Détails bibliographiques
Auteurs principaux: Lee, Eun Seong, Oh, Kyung Taek, Kim, Dongin, Youn, Yu Seok, Bae, You Han
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196406/
https://ncbi.nlm.nih.gov/pubmed/17826863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.08.006
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