Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

Recent studies have shown that protein kinase C (PKC) δ is proteolytically activated at the onset of apoptosis induced by DNA-damaging agents, tumor necrosis factor, and anti-Fas antibody. However, the relationship of PKCδ cleavage to induction of apoptosis is unknown. The present studies demonstrat...

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Bibliographische Detailangaben
Hauptverfasser: Ghayur, Tariq, Hugunin, Margaret, Talanian, Robert V., Ratnofsky, Sheldon, Quinlan, Christopher, Emoto, Yutaka, Pandey, Pramod, Datta, Rakesh, Huang, Yinyin, Kharbanda, Surender, Allen, Hamish, Kamen, Robert, Wong, Winnie, Kufe, Donald
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1996
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196396/
https://ncbi.nlm.nih.gov/pubmed/8976194
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