Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

HIV-1 actively replicates in dendritic cell (DC)-T cell cocultures, but it has been difficult to demonstrate substantial infection of purified mature DCs. We now find that HIV-1 begins reverse transcription much more efficiently in DCs than T cells, even though T cells have higher levels of CD4 and...

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Bibliografiske detaljer
Main Authors: Granelli-Piperno, Angela, Moser, Bernhard, Pope, Melissa, Chen, Dongling, Wei, Yang, Isdell, Frank, O'Doherty, Una, Paxton, William, Koup, Richard, Mojsov, Svetlana, Bhardwaj, Nina, Clark-Lewis, Ian, Baggiolini, Marco, Steinman, Ralph M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1996
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196388/
https://ncbi.nlm.nih.gov/pubmed/8976200
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