Interleukin-5 Expression in the Lung Epithelium of Transgenic Mice Leads to Pulmonary Changes Pathognomonic of Asthma

We have generated transgenic mice that constitutively express murine interleukin (IL)-5 in the lung epithelium. Airway expression of this cytokine resulted in a dramatic accumulation of peribronchial eosinophils and striking pathologic changes including the expansion of bronchusassociated lymphoid t...

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Autores principales: Lee, James J., McGarry, Michael P., Farmer, Steven C., Denzler, Karen L., Larson, Kirsten A., Carrigan, Patricia E., Brenneise, Ina E., Horton, Margaret A., Haczku, Angela, Gelfand, Erwin W., Leikauf, George D., Lee, Nancy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196351/
https://ncbi.nlm.nih.gov/pubmed/9182686
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