Interleukin-5 Expression in the Lung Epithelium of Transgenic Mice Leads to Pulmonary Changes Pathognomonic of Asthma

We have generated transgenic mice that constitutively express murine interleukin (IL)-5 in the lung epithelium. Airway expression of this cytokine resulted in a dramatic accumulation of peribronchial eosinophils and striking pathologic changes including the expansion of bronchusassociated lymphoid t...

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Autors principals: Lee, James J., McGarry, Michael P., Farmer, Steven C., Denzler, Karen L., Larson, Kirsten A., Carrigan, Patricia E., Brenneise, Ina E., Horton, Margaret A., Haczku, Angela, Gelfand, Erwin W., Leikauf, George D., Lee, Nancy A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196351/
https://ncbi.nlm.nih.gov/pubmed/9182686
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