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Signal Transducer and Activator of Transcription-3 (STAT3) Is Constitutively Activated in Normal, Self-renewing B-1 Cells but Only Inducibly Expressed in Conventional B Lymphocytes

Cytokine and growth factor receptor engagement leads to the rapid phosphorylation and activation of latent, cytosolic signal transducers and activators of transcription (STAT) proteins, which then translocate to the nucleus where they regulate transcriptional events from specific promoter sequences....

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Bibliographic Details
Main Authors: Karras, James G., Wang, Zihua, Huo, Li, Howard, Robert G., Frank, David A., Rothstein, Thomas L.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196242/
https://ncbi.nlm.nih.gov/pubmed/9091577
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