Bacterial Lipopolysaccharide Rapidly Inhibits Expression of C–C Chemokine Receptors in Human Monocytes

The present study was designed to investigate the effect of bacterial lipopolysaccharide (LPS) on C–C chemokine receptors (CCR) expressed in human mononuclear phagocytes. LPS caused a rapid and drastic reduction of CCR2 mRNA levels, which binds MCP-1 and -3. CCR1 and CCR5 mRNAs were also reduced, th...

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Bibliografiske detaljer
Main Authors: Sica, Antonio, Saccani, Alessandra, Borsatti, Alessandro, Power, Christine A., Wells, Timothy N.C., Luini, Walter, Polentarutti, Nadia, Sozzani, Silvano, Mantovani, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196159/
https://ncbi.nlm.nih.gov/pubmed/9120403
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