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Mouse Ly-49A Interrupts Early Signaling Events in Natural Killer Cell Cytotoxicity and Functionally Associates with the SHP-1 Tyrosine Phosphatase

The lytic activity of natural killer (NK) cells is inhibited by the expression of class I major histocompatibility complex (MHC) antigens on target cells. In murine NK cells, Ly-49A mediates inhibition of cytotoxicity in response to the class I MHC antigen H-2D(d). In this report, we studied the fun...

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Detalhes bibliográficos
Main Authors: Nakamura, Mary C., Niemi, Eréne C., Fisher, Mark J., Shultz, Leonard D., Seaman, William E., Ryan, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196152/
https://ncbi.nlm.nih.gov/pubmed/9034146
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