Modulation of T-Cell Costimulation as Immunotherapy or Immunochemotherapy in Experimental Visceral Leishmaniasis

CD40 ligand (CD40L)-deficient C57BL/6 mice failed to control intracellular Leishmania donovani visceral infection, indicating that acquired resistance involves CD40-CD40L signaling and costimulation. Conversely, in wild-type C57BL/6 and BALB/c mice with established visceral infection, injection of a...

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Autori principali: Murray, Henry W., Lu, Cristina M., Brooks, Elaine B., Fichtl, Richard E., DeVecchio, Jennifer L., Heinzel, Frederick P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC219611/
https://ncbi.nlm.nih.gov/pubmed/14573667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6453-6462.2003
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