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Developmental Regulation of  VDJ Recombination By the Core Fragment of the T Cell Receptor α Enhancer

The role of T cell receptor α enhancer (E(α)) cis-acting elements in the developmental regulation of VDJ recombination at the TCR α/δ locus was examined in transgenic mice containing variants of a minilocus VDJ recombination substrate. We demonstrate that the 116-bp Tα1,2 core enhancer fragment of t...

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Bibliografiske detaljer
Main Authors: Roberts, Joseph L., Lauzurica, Pilar, Krangel, Michael S.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196107/
https://ncbi.nlm.nih.gov/pubmed/8996249
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