Combined Allogeneic Tumor Cell Vaccination and Systemic Interleukin 12 Prevents Mammary Carcinogenesis in HER-2/neu Transgenic Mice

Transgenic Balb/c mice expressing the transforming rat HER-2/neu oncogene develop early and multifocal mammary carcinomas. Within the first 5 months of life the tissue-specific expression of HER-2/neu causes a progression in all their 10 mammary glands from atypical hyperplasia to invasive carcinoma...

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Autors principals: Nanni, Patrizia, Nicoletti, Giordano, De Giovanni, Carla, Landuzzi, Lorena, Di Carlo, Emma, Cavallo, Federica, Pupa, Serenella M., Rossi, Ilaria, Colombo, Mario P., Ricci, Cinzia, Astolfi, Annalisa, Musiani, Piero, Forni, Guido, Lollini, Pier-Luigi
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195980/
https://ncbi.nlm.nih.gov/pubmed/11696586
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