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Increased Turnover of T Lymphocytes in HIV-1 Infection and Its Reduction by Antiretroviral Therapy

The mechanism of CD4(+) T cell depletion in human immunodeficiency virus (HIV)-1 infection remains controversial. Using deuterated glucose to label the DNA of proliferating cells in vivo, we studied T cell dynamics in four normal subjects and seven HIV-1–infected patients naive to antiretroviral dru...

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Bibliografiske detaljer
Main Authors: Mohri, Hiroshi, Perelson, Alan S., Tung, Keith, Ribeiro, Ruy M., Ramratnam, Bharat, Markowitz, Martin, Kost, Rhonda, Hurley, Weinberger, Leor, Cesar, Denise, Hellerstein, Marc K., Ho, David D.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195973/
https://ncbi.nlm.nih.gov/pubmed/11696593
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