Most α/β T Cell Receptor Diversity Is Due to Terminal Deoxynucleotidyl Transferase

The contribution of template-independent nucleotide addition to antigen receptor diversity is unknown. We therefore determined the size of the T cell receptor (TCR)α/β repertoire in mice bearing a null mutation on both alleles of the terminal deoxynucleotidyl transferase (Tdt) gene. We used a method...

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Detalles Bibliográficos
Main Authors: Cabaniols, Jean-Pierre, Fazilleau, Nicolas, Casrouge, Armanda, Kourilsky, Philippe, Kanellopoulos, Jean M.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
Assuntos:
Brief Definitive Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195970/
https://ncbi.nlm.nih.gov/pubmed/11696602
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