Fuc-Tvii Is Required for T Helper 1 and T Cytotoxic 1 Lymphocyte Selectin Ligand Expression and Recruitment in Inflammation, and Together with Fuc-Tiv Regulates Naive T Cell Trafficking to Lymph Nodes

To determine how the α(1,3)fucosyltransferases Fuc-TIV and Fuc-TVII, and the selectin ligands they control may contribute to the adaptive immune response, contact hypersensitivity (CHS) was characterized in mice deficient in either or both enzymes. We find a substantial CHS deficiency in Fuc-TVII(−/...

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Autors principals: Smithson, Glennda, Rogers, Clare E., Smith, Peter L., Scheidegger, E. Paul, Petryniak, Bronislawa, Myers, Jay T., Kim, David S. L., Homeister, Jonathon W., Lowe, John B.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195944/
https://ncbi.nlm.nih.gov/pubmed/11535629
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