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Protective Role of Raf-1 in Salmonella-Induced Macrophage Apoptosis

Invasive Salmonella induces macrophage apoptosis via the activation of caspase-1 by the bacterial protein SipB. Here we show that infection of macrophages with Salmonella causes the activation and degradation of Raf-1, an important intermediate in macrophage proliferation and activation. Raf-1 degra...

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Bibliografiske detaljer
Main Authors: Jesenberger, Veronika, Procyk, Katarzyna J., Rüth, Jochen, Schreiber, Martin, Theussl, Hans-Christian, Wagner, Erwin F., Baccarini, Manuela
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195927/
https://ncbi.nlm.nih.gov/pubmed/11157055
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