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Negative Selection during the Peripheral Immune Response to Antigen

Thymic selection depends on positive and negative selective mechanisms based on the avidity of T cell interaction with antigen–major histocompatibility complex complexes. However, peripheral mechanisms for the recruitment and clonal expansion of the responding T cell repertoire remain obscure. Here...

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Autors principals: Anderton, Stephen M., Radu, Caius G., Lowrey, Pauline A., Ward, E. Sally, Wraith, David C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195878/
https://ncbi.nlm.nih.gov/pubmed/11136816
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