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A Specific Role of Phosphatidylinositol 3–Kinase γ: A Regulation of Autonomic Ca(2)+ Oscillations in Cardiac Cells
Purinergic stimulation of cardiomyocytes turns on a Src family tyrosine kinase–dependent pathway that stimulates PLCγ and generates IP(3), a breakdown product of phosphatidylinositol 4,5–bisphosphate (PIP2). This signaling pathway closely regulates cardiac cell autonomic activity (i.e., spontaneous...
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Hoofdauteurs: | , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
The Rockefeller University Press
2001
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2195768/ https://ncbi.nlm.nih.gov/pubmed/11266463 |
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