Ribonucleotide Reduction in Mycobacterium tuberculosis: Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases

Mycobacterium tuberculosis, the causative agent of tuberculosis, possesses a class Ib ribonucleotide reductase (RNR), encoded by the nrdE and nrdF2 genes, in addition to a putative class II RNR, encoded by nrdZ. In this study we probed the relative contributions of these RNRs to the growth and persi...

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Autori principali: Dawes, Stephanie S., Warner, Digby F., Tsenova, Liana, Timm, Juliano, McKinney, John D., Kaplan, Gilla, Rubin, Harvey, Mizrahi, Valerie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC219568/
https://ncbi.nlm.nih.gov/pubmed/14573627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6124-6131.2003
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