Human Transporters Associated with Antigen Processing (Taps) Select Epitope Precursor Peptides for Processing in the Endoplasmic Reticulum and Presentation to T Cells

Antigen presentation by major histocompatibility complex (MHC) class I molecules requires peptide supply by the transporters associated with antigen processing (TAPs), which select substrates in a species- and, in the rat, allele-specific manner. Conflicts between TAPs and MHC preferences for COOH-t...

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Autori principali: Lauvau, Grégoire, Kakimi, Kazuhiro, Niedermann, Gabriele, Ostankovitch, Marina, Yotnda, Patricia, Firat, Hüseyin, Chisari, Francis V., van Endert, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195672/
https://ncbi.nlm.nih.gov/pubmed/10544195
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